MLB DFS Picks: DraftKings Plays and Strategy for Tuesday, March 18

This article is part of our DFS MLB series.

Top DFS Pitching and Team Stacking Strategies for DraftKings

In this article, I’m going to take a deeper dive into pitching and team stacking options. Let’s take a look at our optimizer’s rankings of the pitchers for the DraftKings nine-game main slate, sorted by projected fantasy points.

Visit WagerKey’s MLB Daily Lineups to find out where the hitters slot in!

*No postponements expected

Yoshinobu Yamamoto is our lone ace on the slate and is priced $1,000 more than anyone else – and for good reason. His strikeout rate is over 30 percent and is by far the best of the available starters, which has helped lead him to three games of at least 27 DK points over his last five. He’s a worthy choice to spend up on.

We’ve also highlighted Jameson Taillon, Colton Gordon and Randy Vasquez in our optimizer. Our top point-per-dollar option is Vasquez, who draws a matchup against an Angels squad that leads the MLB in strikeout rate at 27.4 percent. Gordon will make his MLB debut and has posted an impressive 2.55 ERA across eight starts in Triple-A. Taillon also draws a nice matchup against the Marlins, who have been held under five runs in six straight. Clay Holmes, Nick Lodolo, Chris Bassitt and Gunnar Hoglund all rank well in the metrics below to give DFS players plenty of options tonight. 

Here’s how each pitcher ranks in key categories (stats are from 2025 season only):

Pitcher Fantasy Points FIP K% Opponent K%

Top DFS Pitching and Team Stacking Strategies for DraftKings

In this article, I’m going to take a deeper dive into pitching and team stacking options. Let’s take a look at our optimizer’s rankings of the pitchers for the DraftKings nine-game main slate, sorted by projected fantasy points.

Visit WagerKey’s MLB Daily Lineups to find out where the hitters slot in!

*No postponements expected

Yoshinobu Yamamoto is our lone ace on the slate and is priced $1,000 more than anyone else – and for good reason. His strikeout rate is over 30 percent and is by far the best of the available starters, which has helped lead him to three games of at least 27 DK points over his last five. He’s a worthy choice to spend up on.

We’ve also highlighted Jameson Taillon, Colton Gordon and Randy Vasquez in our optimizer. Our top point-per-dollar option is Vasquez, who draws a matchup against an Angels squad that leads the MLB in strikeout rate at 27.4 percent. Gordon will make his MLB debut and has posted an impressive 2.55 ERA across eight starts in Triple-A. Taillon also draws a nice matchup against the Marlins, who have been held under five runs in six straight. Clay Holmes, Nick Lodolo, Chris Bassitt and Gunnar Hoglund all rank well in the metrics below to give DFS players plenty of options tonight. 

Here’s how each pitcher ranks in key categories (stats are from 2025 season only):

Pitcher Fantasy Points FIP K% Opponent K%
Yoshinobu Yamamoto 1 3 1 14
Clay Holmes 2 1 3 5
Nick Lodolo 3 5 7 6
Chris Bassitt 4 4 2 7
Jameson Taillon 5 12 8 4
Patrick Corbin 6 9 12 2
Ryan Pepiot 7 11 6 16
Mitchell Parker 8 6 14 8
Colton Gordon 9 N/A N/A 17
Gunnar Hoglund 10 2 4 9
Michael Lorenzen 11 10 5 11
Bryce Elder 12 13 9 12
Randy Vasquez 13 14 15 1
Davis Martin 14 7 11 3
Ryan Weathers 15 N/A N/A 10
Bailey Falter 16 8 10 15
Kyle Hendricks 17 15 13 18
Antonio Senzatela 18 16 16 13

Analyzing Team Stack Rankings for Maximum DFS Impact

Here is how each team ranks in implied runs, BABIP (batting average on balls in play) and how popular we expect each team stack to be in GPPs:

Team Implied Runs BABIP Stack Popularity
Dodgers 6.3 1 High
Rangers 6.2 16 High
Mets 5.8 9 High
Padres 5.8 2 Medium
Reds 5.7 8 High
Braves 5.6 10 High
Cubs 5.1 11 Low
Blue Jays 5.0 7 Medium
Astros 4.7 3 Medium
Royals 4.2 12 High
Nationals 3.8 13 Medium
Angels 3.5 18 Low
Rays 3.4 6 Medium
Rockies 3.2 14 Medium
White Sox 3.1 17 Low
Marlins 2.7 4 Low
Athletics 2.6 5 Low
Pirates 2.5 15 Low

My primary team stack targets

Rockies vs. LHP Corbin (4.62 FIP vs. 3.13 ERA). Key pieces: Hunter Goodman, Kyle Farmer, Brenton Doyle, Jordan Beck, Ryan McMahon

Reds vs. RHP Martin (4.37 FIP, 15.2 K%). Key pieces: Spencer Steer, Santiago Espinal, Elly De La Cruz, Gavin Lux, Austin Hays

Astros vs. RHP Lorenzen (4.63 FIP vs. 3.57 ERA). Key pieces: Yainer Diaz, Christian Walker, Jose Altuve, Jeremy Pena, Isaac Paredes

Nationals vs. RHP Elder (5.21 FIP, 1.9 HR/9). Key pieces: Amed Rosario, Jose Tena, CJ Abrams, Alex Call, James Wood

Key Matchups and Batter vs. Pitcher Insights for DFS Success

Notable hitter matchups against the opposing starter today:

  • Brandon Lowe: 5-for-11, 3 HR; .455 BA, 1.902 OPS
  • Brandon Nimmo: 5-for-12, 1 HR; .417 BA, 1.167 OPS
  • Manny Machado: 9-for-20, 1 2B; .450 BA, .950 OPS
  • Jake Cronenworth: 4-for-13, 1 HR; .308 BA, .973 OPS
  • Ryan McMahon: 7-for-16, 1 2B; .438 BA, .938 OPS

For up-to-the-minute updates on injuries, lineups, roster changes and more, head to WagerKey’s Fantasy Baseball News & Latest MLB Updates or follow @WagerKeyMLB on X.

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